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Michael Marvin, Ph.D., is a tenured associate professor of chemistry in the College of Arts and Sciences.
His research interest is the regulation of gene expression with a focus on the regulation of pre-mRNA splicing by kinases in the model organism fission yeast (S. pombe). Defects in pre-mRNA splicing have been tied to various human diseases such as spinal muscular atrophy (SMA) and a variety of cancers. Fission yeast have many of the same evolutionarily conserved splicing machinery and kinases that exist in humans.
Current research projects being carried out at °Ä¿Í×ãÇò with undergraduates are focusing on how pre-mRNA splicing possibly requires phosphorylation to adapt to various stress conditions that mimic human disease states. These results will be informative for a more in-depth understanding of the essential biological process of pre-mRNA splicing during gene expression and possibly be beneficial to human disease research.
Marvin's teaching interests include a focus on biochemistry lab and lecture courses where the courses are designed to be relevant to pre-health students as well as students entering graduate school in chemistry, biology, biochemistry or related fields.